Official symbol | CDC42EP4 |
Gene id | 23580 |
Organism | Homo sapiens |
Official full symbol | CDC42 effector protein 4 |
Gene type | protein-coding |
Also known as | BORG4, CEP4, KAIA1777 |
Summary | The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. |
Genomic regions | Chromosome 17 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CDC42EP4-201 | ENST00000335793.4 | 3098 | 356aa | Protein coding | CCDS11695 | Q9H3Q1-1 | NM_012121.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
CDC42EP4-202 | ENST00000439510.2 | 2879 | 286aa | Protein coding | - | Q9H3Q1-2 | - | TSL:2, GENCODE basic, |
CDC42EP4-205 | ENST00000580315.1 | 1022 | 127aa | Protein coding | - | J3KRZ9 | - | CDS 3' incomplete, TSL:2, |
CDC42EP4-206 | ENST00000581014.1 | 737 | 79aa | Protein coding | - | J3QR93 | - | TSL:5, GENCODE basic, |
CDC42EP4-204 | ENST00000579611.1 | 580 | 73aa | Protein coding | - | J3QQS6 | - | CDS 3' incomplete, TSL:4, |
CDC42EP4-209 | ENST00000630622.1 | 240 | 79aa | Protein coding | - | J3QR93 | - | TSL:5, GENCODE basic, |
CDC42EP4-208 | ENST00000582303.1 | 660 | No protein | Processed transcript | - | - | - | TSL:5, |
CDC42EP4-203 | ENST00000578516.1 | 572 | No protein | Processed transcript | - | - | - | TSL:4, |
CDC42EP4-207 | ENST00000581045.1 | 539 | No protein | Processed transcript | - | - | - | TSL:4, |
Target Gene | CDC42EP4 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CDC42EP4 had been KO in hela cell line. |
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