Official symbol | CDK19 |
Gene id | 23097 |
Organism | Homo sapiens |
Official full symbol | cyclin dependent kinase 19 |
Gene type | protein-coding |
Also known as | CDC2L6, CDK11, EIEE87, bA346C16.3 |
Summary | This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Genomic regions | Chromosome 6 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CDK19-202 | ENST00000368911.8 | 6399 | 502aa | Protein coding | CCDS5085 | Q9BWU1-1 | NM_015076.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
CDK19-201 | ENST00000323817.7 | 6067 | 442aa | Protein coding | CCDS75503 | Q9BWU1-2 | - | TSL:1, GENCODE basic, |
CDK19-203 | ENST00000413605.6 | 6007 | 398aa | Protein coding | - | F6QTA4 | - | TSL:1, GENCODE basic, |
CDK19-204 | ENST00000457688.5 | 955 | 251aa | Protein coding | - | Q5JQZ9 | - | CDS 3' incomplete, TSL:5, |
CDK19-206 | ENST00000463016.1 | 604 | 122aa | Nonsense mediated decay | - | H0YDW9 | - | CDS 5' incomplete, TSL:5, |
CDK19-208 | ENST00000497709.1 | 1117 | No protein | Processed transcript | - | - | - | TSL:3, |
CDK19-207 | ENST00000468997.5 | 1083 | No protein | Processed transcript | - | - | - | TSL:1, |
CDK19-205 | ENST00000460913.1 | 448 | No protein | Processed transcript | - | - | - | TSL:5, |
Target Gene | CDK19 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CDK19 had been KO in hela cell line. |
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