Official symbol | KDM1A |
Gene id | 23028 |
Organism | Homo sapiens |
Official full symbol | lysine demethylase 1A |
Gene type | protein-coding |
Also known as | AOF2, BHC110, CPRF, KDM1, LSD1 |
Summary | This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
KDM1A-202 | ENST00000400181.9 | 3085 | 876aa | Protein coding | CCDS53278 | O60341-2 | NM_001009999.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
KDM1A-203 | ENST00000465864.2 | 3039 | 858aa | Protein coding | CCDS85939 | R4GMQ1 | - | TSL:5, GENCODE basic, |
KDM1A-201 | ENST00000356634.7 | 3033 | 852aa | Protein coding | CCDS30627 | O60341-1 | - | TSL:1, GENCODE basic, |
KDM1A-205 | ENST00000494920.1 | 905 | 301aa | Protein coding | - | R4GMP9 | - | CDS 5' and 3' incomplete, TSL:3, |
KDM1A-206 | ENST00000602503.1 | 2810 | No protein | Retained intron | - | - | - | TSL:NA, |
KDM1A-204 | ENST00000481879.1 | 525 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | KDM1A |
This KO Strategy | loading |
Red Cotton™ Notes | Gene KDM1A had been KO in hela cell line. |
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