Official symbol | PTGR1 |
Gene id | 22949 |
Organism | Homo sapiens |
Official full symbol | prostaglandin reductase 1 |
Gene type | protein-coding |
Also known as | LTB4DH, PGR1, ZADH3 |
Summary | This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. |
Genomic regions | Chromosome 9 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PTGR1-205 | ENST00000407693.7 | 1599 | 329aa | Protein coding | CCDS6779 | Q14914-1 | NM_001146108.2 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PTGR1-201 | ENST00000309195.9 | 1223 | 329aa | Protein coding | CCDS6779 | Q14914-1 | - | TSL:1, GENCODE basic, APPRIS P1, |
PTGR1-209 | ENST00000538962.7 | 1200 | 301aa | Protein coding | CCDS55331 | Q14914-2 | - | TSL:2, GENCODE basic, |
PTGR1-206 | ENST00000422125.1 | 461 | 119aa | Protein coding | - | Q5JVP2 | - | CDS 3' incomplete, TSL:3, |
PTGR1-204 | ENST00000374324.5 | 2298 | 73aa | Nonsense mediated decay | - | F6XGT7 | - | TSL:5, |
PTGR1-207 | ENST00000466771.6 | 1941 | 300aa | Nonsense mediated decay | - | F2Z3J9 | - | TSL:3, |
PTGR1-203 | ENST00000374313.5 | 1061 | No protein | Retained intron | - | - | - | TSL:1, |
PTGR1-202 | ENST00000374308.1 | 847 | No protein | Retained intron | - | - | - | TSL:2, |
PTGR1-208 | ENST00000485319.1 | 389 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | PTGR1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PTGR1 had been KO in hela cell line. |
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