Official symbol | PPP6R1 |
Gene id | 22870 |
Organism | Homo sapiens |
Official full symbol | protein phosphatase 6 regulatory subunit 1 |
Gene type | protein-coding |
Also known as | KIAA1115, PP6R1, SAP190, SAPS1 |
Summary | Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 ). |
Genomic regions | Chromosome 19 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PPP6R1-201 | ENST00000412770.7 | 3984 | 881aa | Protein coding | CCDS46186 | Q9UPN7 | NM_014931.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PPP6R1-203 | ENST00000587283.5 | 2953 | 881aa | Protein coding | CCDS46186 | Q9UPN7 | - | TSL:1, GENCODE basic, APPRIS P1, |
PPP6R1-208 | ENST00000592242.1 | 574 | 157aa | Protein coding | - | K7EM28 | - | CDS 3' incomplete, TSL:4, |
PPP6R1-204 | ENST00000587457.1 | 2389 | No protein | Retained intron | - | - | - | TSL:2, |
PPP6R1-205 | ENST00000589343.1 | 904 | No protein | Retained intron | - | - | - | TSL:2, |
PPP6R1-206 | ENST00000591323.5 | 848 | No protein | Retained intron | - | - | - | TSL:3, |
PPP6R1-202 | ENST00000586690.1 | 668 | No protein | Retained intron | - | - | - | TSL:2, |
PPP6R1-207 | ENST00000591602.1 | 520 | No protein | Retained intron | - | - | - | TSL:5, |
Target Gene | PPP6R1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PPP6R1 had been KO in hek293t cell line. |
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