Official symbol | MRAS |
Gene id | 22808 |
Organism | Homo sapiens |
Official full symbol | muscle RAS oncogene homolog |
Gene type | protein-coding |
Also known as | M-RAs, NS11, R-RAS3, RRAS3 |
Summary | This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Genomic regions | Chromosome 3 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
MRAS-201 | ENST00000289104.8 | 4538 | 208aa | Protein coding | CCDS3100 | O14807-1 | - | TSL:2, GENCODE basic, APPRIS P1, |
MRAS-210 | ENST00000614350.4 | 4377 | 132aa | Protein coding | CCDS58855 | O14807-2 | - | TSL:2, GENCODE basic, |
MRAS-202 | ENST00000423968.7 | 4098 | 208aa | Protein coding | CCDS3100 | O14807-1 | NM_001085049.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
MRAS-211 | ENST00000621127.4 | 3801 | 132aa | Protein coding | CCDS58855 | O14807-2 | - | TSL:5, GENCODE basic, |
MRAS-204 | ENST00000464896.5 | 1534 | 132aa | Protein coding | CCDS58855 | O14807-2 | - | TSL:2, GENCODE basic, |
MRAS-205 | ENST00000474559.1 | 856 | 208aa | Protein coding | CCDS3100 | O14807-1 | - | TSL:3, GENCODE basic, APPRIS P1, |
MRAS-209 | ENST00000494949.5 | 431 | 107aa | Protein coding | - | C9J8Q6 | - | CDS 3' incomplete, TSL:5, |
MRAS-206 | ENST00000475711.5 | 271 | 23aa | Protein coding | - | C9J601 | - | CDS 3' incomplete, TSL:3, |
MRAS-203 | ENST00000461114.1 | 973 | No protein | Processed transcript | - | - | - | TSL:2, |
MRAS-207 | ENST00000477784.1 | 394 | No protein | Processed transcript | - | - | - | TSL:3, |
MRAS-208 | ENST00000478647.1 | 429 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | MRAS |
This KO Strategy | loading |
Red Cotton™ Notes | Gene MRAS had been KO in hela cell line. |
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