CRISPR-U™ Gene Knockout Cell Line Strategy

FGF11 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human FGF11 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol FGF11
Gene id 2256
Organism Homo sapiens
Official full symbol fibroblast growth factor 11
Gene type protein-coding
Also known as FGF-11, FHF-3, FHF3
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants.
Genomic regions Chromosome 17
Strategy Summary
This gene has 5 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
FGF11-201 ENST00000293829.9 2578 225aa Protein coding CCDS11105 Q92914 NM_004112.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
FGF11-202 ENST00000572907.5 2358 101aa Protein coding - I3L4N4 - TSL:1, GENCODE basic,
FGF11-203 ENST00000575082.5 2315 101aa Protein coding - I3L4N4 - TSL:2, GENCODE basic,
FGF11-205 ENST00000575398.5 990 101aa Protein coding - I3L4N4 - TSL:2, GENCODE basic,
FGF11-204 ENST00000575235.5 928 101aa Protein coding - I3L4N4 - TSL:1, GENCODE basic,
FGF11-206 ENST00000576328.1 912 No protein Retained intron - - - TSL:1,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene FGF11
This KO Strategy loading
Red Cotton™ Notes Gene FGF11 had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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