Official symbol | FCER2 |
Gene id | 2208 |
Organism | Homo sapiens |
Official full symbol | Fc fragment of IgE receptor II |
Gene type | protein-coding |
Also known as | BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF |
Summary | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Genomic regions | Chromosome 19 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
FCER2-201 | ENST00000346664.9 | 1596 | 321aa | Protein coding | CCDS12184 | P06734 | - | TSL:1, GENCODE basic, APPRIS P2, |
FCER2-205 | ENST00000597921.6 | 1585 | 321aa | Protein coding | CCDS12184 | P06734 | NM_001220500.2 | TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92, |
FCER2-202 | ENST00000360067.8 | 1482 | 320aa | Protein coding | - | K3W4U1 | - | TSL:5, GENCODE basic, APPRIS ALT2, |
FCER2-203 | ENST00000593418.1 | 801 | 159aa | Protein coding | - | M0R1R5 | - | CDS 3' incomplete, TSL:3, |
FCER2-204 | ENST00000597312.5 | 1910 | No protein | Retained intron | - | - | - | TSL:2, |
FCER2-207 | ENST00000598803.5 | 1872 | No protein | Retained intron | - | - | - | TSL:2, |
FCER2-206 | ENST00000597934.1 | 1577 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | FCER2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene FCER2 had been KO in hela cell line. |
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