Official symbol | FLCN |
Gene id | 201163 |
Organism | Homo sapiens |
Official full symbol | folliculin |
Gene type | protein-coding |
Also known as | BHD, DENND8B, FLCL |
Summary | This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Genomic regions | Chromosome 17 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
FLCN-201 | ENST00000285071.9 | 3667 | 579aa | Protein coding | CCDS32579 | Q8NFG4-1 | NM_144997.7 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
FLCN-203 | ENST00000389169.9 | 1692 | 342aa | Protein coding | CCDS32580 | Q8NFG4-2 | - | TSL:1, GENCODE basic, |
FLCN-205 | ENST00000417064.1 | 757 | 153aa | Protein coding | - | C9J4C4 | - | CDS 3' incomplete, TSL:2, |
FLCN-206 | ENST00000461699.1 | 243 | 37aa | Protein coding | - | J3QQZ7 | - | CDS 3' incomplete, TSL:3, |
FLCN-202 | ENST00000389168.6 | 3359 | No protein | Retained intron | - | - | - | TSL:2, |
FLCN-207 | ENST00000466317.1 | 2684 | No protein | Retained intron | - | - | - | TSL:2, |
FLCN-204 | ENST00000389171.4 | 2523 | No protein | Retained intron | - | - | - | TSL:2, |
FLCN-209 | ENST00000480316.1 | 786 | No protein | Retained intron | - | - | - | TSL:2, |
FLCN-208 | ENST00000473853.1 | 384 | No protein | Retained intron | - | - | - | TSL:5, |
FLCN-210 | ENST00000577591.1 | 296 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | FLCN |
This KO Strategy | loading |
Red Cotton™ Notes | Gene FLCN had been KO in hela cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×