Official symbol | CSF1 |
Gene id | 1435 |
Organism | Homo sapiens |
Official full symbol | colony stimulating factor 1 |
Gene type | protein-coding |
Also known as | CSF-1, MCSF |
Summary | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CSF1-201 | ENST00000329608.11 | 3994 | 554aa | Protein coding | CCDS816 | P09603-1 | NM_000757.6 | TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92, |
CSF1-204 | ENST00000369802.7 | 2484 | 554aa | Protein coding | CCDS816 | P09603-1 | - | TSL:1, GENCODE basic, APPRIS P4, |
CSF1-203 | ENST00000369801.1 | 1364 | 438aa | Protein coding | CCDS817 | P09603-2 | - | TSL:1, GENCODE basic, APPRIS ALT2, |
CSF1-205 | ENST00000420111.6 | 1083 | 256aa | Protein coding | CCDS30797 | P09603-3 | - | TSL:5, GENCODE basic, APPRIS ALT2, |
CSF1-206 | ENST00000488198.5 | 1009 | 285aa | Protein coding | - | E9PJA2 | - | CDS 3' incomplete, TSL:3, |
CSF1-202 | ENST00000357302.8 | 597 | 119aa | Protein coding | - | H7BY18 | - | CDS 3' incomplete, TSL:3, |
CSF1-209 | ENST00000527192.5 | 577 | 150aa | Protein coding | - | E9PQ08 | - | CDS 3' incomplete, TSL:4, |
CSF1-207 | ENST00000525659.5 | 551 | 113aa | Protein coding | - | E9PKP4 | - | CDS 3' incomplete, TSL:4, |
CSF1-208 | ENST00000526001.1 | 573 | No protein | Processed transcript | - | - | - | TSL:4, |
Target Gene | CSF1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CSF1 had been KO in hela cell line. |
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