CRISPR-U™ Gene Knockout Cell Line Strategy

CMPK2 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human CMPK2 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol CMPK2
Gene id 129607
Organism Homo sapiens
Official full symbol cytidine/uridine monophosphate kinase 2
Gene type protein-coding
Also known as NDK, TMPK2, TYKi, UMP-CMPK2
Summary This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene.
Genomic regions Chromosome 2
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
CMPK2-201 ENST00000256722.10 3095 449aa Protein coding CCDS42648 Q5EBM0-1 NM_207315.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
CMPK2-202 ENST00000404168.1 2042 409aa Protein coding CCDS58696 Q5EBM0-4 - TSL:1, GENCODE basic,
CMPK2-203 ENST00000458098.5 1224 366aa Protein coding CCDS58695 Q5EBM0-3 - TSL:1, GENCODE basic,
CMPK2-206 ENST00000478738.5 2417 No protein Processed transcript - - - TSL:2,
CMPK2-204 ENST00000465619.5 722 No protein Processed transcript - - - TSL:5,
CMPK2-207 ENST00000491738.5 569 No protein Processed transcript - - - TSL:4,
CMPK2-205 ENST00000470479.1 565 No protein Processed transcript - - - TSL:4,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene CMPK2
This KO Strategy loading
Red Cotton™ Notes Gene CMPK2 had been KO in a549 cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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