Official symbol | CLK1 |
Gene id | 1195 |
Organism | Homo sapiens |
Official full symbol | CDC like kinase 1 |
Gene type | protein-coding |
Also known as | CLK, CLK/STY, STY |
Summary | This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. |
Genomic regions | Chromosome 2 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CLK1-205 | ENST00000434813.3 | 2026 | 526aa | Protein coding | CCDS54427 | P49759-3 | - | TSL:2, GENCODE basic, |
CLK1-201 | ENST00000321356.9 | 1847 | 484aa | Protein coding | CCDS2331 | P49759-1 | NM_004071.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
CLK1-215 | ENST00000621181.4 | 1843 | 454aa | Protein coding | - | A0A087WVK0 | - | TSL:1, GENCODE basic, |
CLK1-203 | ENST00000409769.6 | 1192 | 307aa | Protein coding | - | B8ZZR0 | - | TSL:2, GENCODE basic, |
CLK1-204 | ENST00000432425.5 | 1682 | 136aa | Nonsense mediated decay | - | P49759-2 | - | TSL:1, |
CLK1-202 | ENST00000409403.6 | 1664 | 355aa | Nonsense mediated decay | - | F8WBF5 | - | TSL:5, |
CLK1-213 | ENST00000492793.1 | 596 | No protein | Processed transcript | - | - | - | TSL:4, |
CLK1-210 | ENST00000473565.5 | 3208 | No protein | Retained intron | - | - | - | TSL:1, |
CLK1-207 | ENST00000461981.5 | 3173 | No protein | Retained intron | - | - | - | TSL:2, |
CLK1-211 | ENST00000481641.1 | 690 | No protein | Retained intron | - | - | - | TSL:4, |
CLK1-212 | ENST00000482590.1 | 626 | No protein | Retained intron | - | - | - | TSL:2, |
CLK1-208 | ENST00000464454.1 | 484 | No protein | Retained intron | - | - | - | TSL:2, |
CLK1-214 | ENST00000496205.1 | 480 | No protein | Retained intron | - | - | - | TSL:2, |
CLK1-209 | ENST00000472679.1 | 461 | No protein | Retained intron | - | - | - | TSL:2, |
CLK1-206 | ENST00000461326.1 | 435 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | CLK1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CLK1 had been KO in hela cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×