CRISPR-U™ Gene Knockout Cell Line Strategy

HNRNPUL1 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human HNRNPUL1 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol HNRNPUL1
Gene id 11100
Organism Homo sapiens
Official full symbol heterogeneous nuclear ribonucleoprotein U like 1
Gene type protein-coding
Also known as E1B-AP5, E1BAP5, HNRPUL1
Summary This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells.
Genomic regions Chromosome 19
Strategy Summary
This gene has 15 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
HNRNPUL1-204 ENST00000392006.8 3925 856aa Protein coding CCDS12576 Q9BUJ2-1 NM_007040.6 TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92,
HNRNPUL1-201 ENST00000263367.7 2952 767aa Protein coding CCDS82351 B7Z4B8 - TSL:2, GENCODE basic,
HNRNPUL1-207 ENST00000595018.5 2794 756aa Protein coding CCDS12577 Q9BUJ2-4 - TSL:2, GENCODE basic,
HNRNPUL1-205 ENST00000593587.5 2725 756aa Protein coding CCDS12577 Q9BUJ2-4 - TSL:2, GENCODE basic,
HNRNPUL1-202 ENST00000352456.7 3426 766aa Protein coding - A0A0A0MRA5 - TSL:1, GENCODE basic,
HNRNPUL1-220 ENST00000602130.5 2932 804aa Protein coding - Q9BUJ2-2 - TSL:1, GENCODE basic, APPRIS ALT2,
HNRNPUL1-203 ENST00000378215.8 2864 752aa Protein coding - Q9BUJ2-3 - TSL:2, GENCODE basic,
HNRNPUL1-213 ENST00000599614.5 2447 641aa Protein coding - M0R3F1 - CDS 5' incomplete, TSL:5,
HNRNPUL1-214 ENST00000599719.5 1473 371aa Protein coding - M0QYZ0 - CDS 3' incomplete, TSL:1,
HNRNPUL1-221 ENST00000617305.4 1018 122aa Protein coding - A0A087X1I2 - TSL:1, GENCODE basic,
HNRNPUL1-219 ENST00000601336.5 754 158aa Protein coding - M0R0K8 - CDS 3' incomplete, TSL:2,
HNRNPUL1-218 ENST00000601309.5 672 118aa Protein coding - M0QZV6 - CDS 3' incomplete, TSL:5,
HNRNPUL1-211 ENST00000597725.5 573 172aa Protein coding - M0QYI8 - CDS 3' incomplete, TSL:4,
HNRNPUL1-222 ENST00000617774.1 451 122aa Protein coding - A0A087X1I2 - TSL:5, GENCODE basic,
HNRNPUL1-209 ENST00000595336.1 393 81aa Protein coding - M0R203 - CDS 3' incomplete, TSL:2,
HNRNPUL1-208 ENST00000595196.5 3043 105aa Nonsense mediated decay - M0R247 - TSL:1,
HNRNPUL1-215 ENST00000600332.1 644 26aa Nonsense mediated decay - M0QYG9 - CDS 5' incomplete, TSL:3,
HNRNPUL1-217 ENST00000600596.1 581 90aa Nonsense mediated decay - M0QYM5 - CDS 5' incomplete, TSL:5,
HNRNPUL1-206 ENST00000594207.1 816 No protein Processed transcript - - - TSL:5,
HNRNPUL1-216 ENST00000600493.1 531 No protein Processed transcript - - - TSL:4,
HNRNPUL1-210 ENST00000595806.1 1659 No protein Retained intron - - - TSL:2,
HNRNPUL1-212 ENST00000599521.1 336 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
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Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene HNRNPUL1
This KO Strategy loading
Red Cotton™ Notes Gene HNRNPUL1 had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
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