Official symbol | PLK2 |
Gene id | 10769 |
Organism | Homo sapiens |
Official full symbol | polo like kinase 2 |
Gene type | protein-coding |
Also known as | SNK, hPlk2, hSNK |
Summary | The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Genomic regions | Chromosome 5 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PLK2-215 | ENST00000617412.1 | 2792 | 671aa | Protein coding | CCDS75250 | A0A087WUH9 | - | TSL:5, GENCODE basic, |
PLK2-201 | ENST00000274289.8 | 2786 | 685aa | Protein coding | CCDS3974 | A0A024QZV1 Q9NYY3 | NM_006622.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PLK2-202 | ENST00000502671.5 | 768 | No protein | Processed transcript | - | - | - | TSL:5, |
PLK2-214 | ENST00000515415.5 | 1410 | No protein | Retained intron | - | - | - | TSL:5, |
PLK2-213 | ENST00000514306.1 | 823 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-205 | ENST00000503713.1 | 690 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-206 | ENST00000504196.1 | 625 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-211 | ENST00000510629.1 | 591 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-204 | ENST00000503378.1 | 587 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-209 | ENST00000509422.1 | 580 | No protein | Retained intron | - | - | - | TSL:4, |
PLK2-208 | ENST00000508300.1 | 558 | No protein | Retained intron | - | - | - | TSL:3, |
PLK2-207 | ENST00000505244.1 | 557 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-210 | ENST00000509555.5 | 556 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-203 | ENST00000503115.5 | 536 | No protein | Retained intron | - | - | - | TSL:2, |
PLK2-212 | ENST00000511326.1 | 275 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | PLK2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PLK2 had been KO in hct116 cell line. |
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