Official symbol | STAG2 |
Gene id | 10735 |
Organism | Homo sapiens |
Official full symbol | stromal antigen 2 |
Gene type | protein-coding |
Also known as | HPE13, MKMS, NEDXCF, SA-2, SA2, SCC3B, bA517O1.1 |
Summary | The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Genomic regions | Chromosome X |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
STAG2-203 | ENST00000371145.8 | 6179 | 1268aa | Protein coding | CCDS43990 | Q8N3U4-2 | NM_001042750.2 | TSL:1, GENCODE basic, APPRIS ALT1, MANE Select v0.92, |
STAG2-205 | ENST00000371160.5 | 6045 | 1231aa | Protein coding | CCDS14607 | Q8N3U4-1 | - | TSL:1, GENCODE basic, APPRIS P3, |
STAG2-204 | ENST00000371157.7 | 5991 | 1231aa | Protein coding | CCDS14607 | Q8N3U4-1 | - | TSL:1, GENCODE basic, APPRIS P3, |
STAG2-201 | ENST00000218089.13 | 5218 | 1268aa | Protein coding | CCDS43990 | Q8N3U4-2 | - | TSL:1, GENCODE basic, APPRIS ALT1, |
STAG2-202 | ENST00000371144.7 | 4281 | 1231aa | Protein coding | CCDS14607 | Q8N3U4-1 | - | TSL:1, GENCODE basic, APPRIS P3, |
STAG2-211 | ENST00000455404.5 | 2089 | 548aa | Protein coding | - | B1AMT4 | - | CDS 3' incomplete, TSL:5, |
STAG2-210 | ENST00000435215.5 | 798 | 207aa | Protein coding | - | B1AMT3 | - | CDS 3' incomplete, TSL:5, |
STAG2-209 | ENST00000435103.5 | 742 | 154aa | Protein coding | - | B1AMT1 | - | CDS 3' incomplete, TSL:5, |
STAG2-208 | ENST00000428941.5 | 678 | 169aa | Protein coding | - | B1AMT2 | - | CDS 3' incomplete, TSL:3, |
STAG2-207 | ENST00000394478.1 | 676 | 115aa | Protein coding | - | B1AMT0 | - | CDS 3' incomplete, TSL:5, |
STAG2-206 | ENST00000394477.5 | 385 | 70aa | Protein coding | - | B1AMS9 | - | CDS 3' incomplete, TSL:5, |
STAG2-213 | ENST00000458700.5 | 296 | 40aa | Protein coding | - | B1AMS8 | - | CDS 3' incomplete, TSL:5, |
STAG2-212 | ENST00000458176.5 | 845 | 58aa | Nonsense mediated decay | - | E7ERE6 | - | TSL:3, |
STAG2-215 | ENST00000469481.1 | 989 | No protein | Processed transcript | - | - | - | TSL:3, |
STAG2-214 | ENST00000466748.5 | 873 | No protein | Processed transcript | - | - | - | TSL:5, |
STAG2-218 | ENST00000483575.5 | 864 | No protein | Processed transcript | - | - | - | TSL:5, |
STAG2-216 | ENST00000471107.1 | 709 | No protein | Processed transcript | - | - | - | TSL:5, |
STAG2-217 | ENST00000475602.1 | 356 | No protein | Processed transcript | - | - | - | TSL:3, |
Target Gene | STAG2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene STAG2 had been KO in hela cell line. |
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