Official symbol | STAMBP |
Gene id | 10617 |
Organism | Homo sapiens |
Official full symbol | STAM binding protein |
Gene type | protein-coding |
Also known as | AMSH, MICCAP |
Summary | Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. |
Genomic regions | Chromosome 2 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
STAMBP-202 | ENST00000394070.7 | 6746 | 424aa | Protein coding | CCDS1929 | O95630-1 | NM_213622.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
STAMBP-203 | ENST00000394073.5 | 6386 | 424aa | Protein coding | CCDS1929 | O95630-1 | - | TSL:1, GENCODE basic, APPRIS P1, |
STAMBP-201 | ENST00000339566.7 | 6277 | 424aa | Protein coding | CCDS1929 | O95630-1 | - | TSL:5, GENCODE basic, APPRIS P1, |
STAMBP-204 | ENST00000409707.5 | 1649 | 424aa | Protein coding | CCDS1929 | O95630-1 | - | TSL:5, GENCODE basic, APPRIS P1, |
STAMBP-206 | ENST00000432295.6 | 1156 | 318aa | Protein coding | - | C9JK83 | - | CDS 3' incomplete, TSL:5, |
STAMBP-211 | ENST00000536064.1 | 845 | 209aa | Protein coding | - | F5H5B9 | - | TSL:5, GENCODE basic, |
STAMBP-205 | ENST00000424659.5 | 583 | 163aa | Protein coding | - | C9JEK5 | - | CDS 3' incomplete, TSL:3, |
STAMBP-207 | ENST00000452725.5 | 560 | 137aa | Protein coding | - | C9JZ93 | - | CDS 3' incomplete, TSL:4, |
STAMBP-209 | ENST00000486458.1 | 1012 | No protein | Processed transcript | - | - | - | TSL:3, |
STAMBP-208 | ENST00000478946.1 | 955 | No protein | Processed transcript | - | - | - | TSL:3, |
STAMBP-210 | ENST00000487811.1 | 695 | No protein | Processed transcript | - | - | - | TSL:3, |
Target Gene | STAMBP |
This KO Strategy | loading |
Red Cotton™ Notes | Gene STAMBP had been KO in hela cell line. |
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