CRISPR-U™ Gene Knockout Cell Line Strategy

STAMBP Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human STAMBP Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol STAMBP
Gene id 10617
Organism Homo sapiens
Official full symbol STAM binding protein
Gene type protein-coding
Also known as AMSH, MICCAP
Summary Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Genomic regions Chromosome 2
Strategy Summary
This gene has 8 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
STAMBP-202 ENST00000394070.7 6746 424aa Protein coding CCDS1929 O95630-1 NM_213622.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
STAMBP-203 ENST00000394073.5 6386 424aa Protein coding CCDS1929 O95630-1 - TSL:1, GENCODE basic, APPRIS P1,
STAMBP-201 ENST00000339566.7 6277 424aa Protein coding CCDS1929 O95630-1 - TSL:5, GENCODE basic, APPRIS P1,
STAMBP-204 ENST00000409707.5 1649 424aa Protein coding CCDS1929 O95630-1 - TSL:5, GENCODE basic, APPRIS P1,
STAMBP-206 ENST00000432295.6 1156 318aa Protein coding - C9JK83 - CDS 3' incomplete, TSL:5,
STAMBP-211 ENST00000536064.1 845 209aa Protein coding - F5H5B9 - TSL:5, GENCODE basic,
STAMBP-205 ENST00000424659.5 583 163aa Protein coding - C9JEK5 - CDS 3' incomplete, TSL:3,
STAMBP-207 ENST00000452725.5 560 137aa Protein coding - C9JZ93 - CDS 3' incomplete, TSL:4,
STAMBP-209 ENST00000486458.1 1012 No protein Processed transcript - - - TSL:3,
STAMBP-208 ENST00000478946.1 955 No protein Processed transcript - - - TSL:3,
STAMBP-210 ENST00000487811.1 695 No protein Processed transcript - - - TSL:3,
Ubigene Red Cotton Transcript
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Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene STAMBP
This KO Strategy loading
Red Cotton™ Notes Gene STAMBP had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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