CRISPR-U™ Gene Knockout Cell Line Strategy

FAM3C Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human FAM3C Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol FAM3C
Gene id 10447
Organism Homo sapiens
Official full symbol FAM3 metabolism regulating signaling molecule C
Gene type protein-coding
Also known as GS3786, ILEI
Summary This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells.
Genomic regions Chromosome 7
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
FAM3C-201 ENST00000359943.8 2455 227aa Protein coding CCDS5782 Q92520 NM_014888.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
FAM3C-203 ENST00000426156.1 662 109aa Protein coding - C9JP35 - CDS 3' incomplete, TSL:5,
FAM3C-202 ENST00000412653.5 561 151aa Protein coding - C9JMN4 - CDS 3' incomplete, TSL:4,
FAM3C-205 ENST00000497622.1 666 No protein Retained intron - - - TSL:2,
FAM3C-204 ENST00000474082.1 567 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene FAM3C
This KO Strategy loading
Red Cotton™ Notes Gene FAM3C had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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