Official symbol | CD2BP2 |
Gene id | 10421 |
Organism | Homo sapiens |
Official full symbol | CD2 cytoplasmic tail binding protein 2 |
Gene type | protein-coding |
Also known as | FWP010, LIN1, PPP1R59, Snu40, U5-52K |
Summary | This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. |
Genomic regions | Chromosome 16 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CD2BP2-201 | ENST00000305596.8 | 3361 | 341aa | Protein coding | CCDS10675 | A0A024QZC1 O95400 | NM_006110.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
CD2BP2-203 | ENST00000569466.1 | 1417 | 341aa | Protein coding | CCDS10675 | A0A024QZC1 O95400 | - | TSL:1, GENCODE basic, APPRIS P1, |
CD2BP2-202 | ENST00000564525.1 | 541 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | CD2BP2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CD2BP2 had been KO in hek293t cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×