Official symbol | IRF9 |
Gene id | 10379 |
Organism | Homo sapiens |
Official full symbol | interferon regulatory factor 9 |
Gene type | protein-coding |
Also known as | IRF-9, ISGF3, ISGF3G, p48 |
Summary | This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Mutations in this gene result in Immunodeficiency 65. |
Genomic regions | Chromosome 14 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
IRF9-202 | ENST00000396864.8 | 1626 | 393aa | Protein coding | CCDS9615 | Q00978 | NM_006084.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
IRF9-203 | ENST00000557894.5 | 1391 | 353aa | Protein coding | - | H0YMB0 | - | TSL:5, GENCODE basic, |
IRF9-207 | ENST00000560275.5 | 841 | 267aa | Protein coding | - | H0YNP4 | - | CDS 3' incomplete, TSL:5, |
IRF9-201 | ENST00000324076.4 | 658 | 209aa | Protein coding | - | H7BXP4 | - | CDS 5' incomplete, TSL:5, |
IRF9-205 | ENST00000559284.5 | 583 | 178aa | Protein coding | - | H0YMB6 | - | CDS 3' incomplete, TSL:5, |
IRF9-213 | ENST00000561342.5 | 1066 | 50aa | Nonsense mediated decay | - | H0YNM9 | - | TSL:5, |
IRF9-211 | ENST00000560852.1 | 731 | 50aa | Nonsense mediated decay | - | H0YNM9 | - | TSL:3, |
IRF9-215 | ENST00000561415.1 | 1769 | No protein | Retained intron | - | - | - | TSL:2, |
IRF9-210 | ENST00000560542.1 | 819 | No protein | Retained intron | - | - | - | TSL:2, |
IRF9-208 | ENST00000560311.1 | 648 | No protein | Retained intron | - | - | - | TSL:2, |
IRF9-209 | ENST00000560365.5 | 623 | No protein | Retained intron | - | - | - | TSL:2, |
IRF9-214 | ENST00000561412.1 | 608 | No protein | Retained intron | - | - | - | TSL:5, |
IRF9-206 | ENST00000559863.1 | 573 | No protein | Retained intron | - | - | - | TSL:3, |
IRF9-204 | ENST00000559229.1 | 567 | No protein | Retained intron | - | - | - | TSL:2, |
IRF9-212 | ENST00000561009.5 | 546 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | IRF9 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene IRF9 had been KO in hela cell line. |
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