CRISPR-U™ Gene Knockout Cell Line Strategy

HNRNPR Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human HNRNPR Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol HNRNPR
Gene id 10236
Organism Homo sapiens
Official full symbol heterogeneous nuclear ribonucleoprotein R
Gene type protein-coding
Also known as HNRPR, hnRNP-R
Summary This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10.
Genomic regions Chromosome 1
Strategy Summary
This gene has 10 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
HNRNPR-201 ENST00000302271.11 7751 633aa Protein coding CCDS232 O43390-1 NM_005826.5 TSL:1, GENCODE basic, APPRIS P3, MANE Select v0.92,
HNRNPR-210 ENST00000478691.5 7646 535aa Protein coding CCDS60020 O43390-4 - TSL:1, GENCODE basic,
HNRNPR-202 ENST00000374612.5 2694 633aa Protein coding CCDS232 O43390-1 - TSL:5, GENCODE basic, APPRIS P3,
HNRNPR-203 ENST00000374616.7 2691 636aa Protein coding CCDS44085 O43390-2 - TSL:1, GENCODE basic, APPRIS ALT1,
HNRNPR-212 ENST00000606561.5 1837 494aa Protein coding CCDS72726 B4DT28 - TSL:2, GENCODE basic,
HNRNPR-204 ENST00000427764.3 1788 595aa Protein coding CCDS72727 O43390-3 - TSL:1, GENCODE basic,
HNRNPR-214 ENST00000675048.1 2099 481aa Protein coding - - - GENCODE basic,
HNRNPR-208 ENST00000476451.2 1032 238aa Protein coding - - - CDS 3' incomplete, TSL:4,
HNRNPR-205 ENST00000463552.5 837 279aa Protein coding - - - CDS 5' and 3' incomplete, TSL:4,
HNRNPR-207 ENST00000470941.5 560 186aa Protein coding - - - CDS 5' and 3' incomplete, TSL:4,
HNRNPR-213 ENST00000641107.1 646 141aa Nonsense mediated decay - A0A286YEZ8 - CDS 5' incomplete,
HNRNPR-209 ENST00000476660.1 1637 No protein Processed transcript - - - TSL:1,
HNRNPR-206 ENST00000464516.1 557 No protein Processed transcript - - - TSL:2,
HNRNPR-211 ENST00000490652.1 612 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene HNRNPR
This KO Strategy loading
Red Cotton™ Notes Gene HNRNPR had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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