CRISPR-U™ Gene Knockout Cell Line Strategy

CDK3 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human CDK3 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol CDK3
Gene id 1018
Organism Homo sapiens
Official full symbol cyclin dependent kinase 3
Gene type protein-coding
Summary This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0.
Genomic regions Chromosome 17
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
CDK3-201 ENST00000425876.6 1582 305aa Protein coding CCDS11736 Q00526 - TSL:1, GENCODE basic, APPRIS P1,
CDK3-202 ENST00000448471.2 1570 305aa Protein coding CCDS11736 Q00526 - TSL:5, GENCODE basic, APPRIS P1,
CDK3-203 ENST00000586261.2 803 213aa Protein coding - K7EJ83 - CDS 3' incomplete, TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene CDK3
This KO Strategy loading
Red Cotton™ Notes Gene CDK3 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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