Official symbol | PARP3 |
Gene id | 10039 |
Organism | Homo sapiens |
Official full symbol | poly(ADP-ribose) polymerase family member 3 |
Gene type | protein-coding |
Also known as | ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3 |
Summary | The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Genomic regions | Chromosome 3 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PARP3-202 | ENST00000417220.6 | 2472 | 533aa | Protein coding | CCDS43097 | Q9Y6F1-1 | - | TSL:5, GENCODE basic, APPRIS P1, |
PARP3-206 | ENST00000471971.6 | 2393 | 533aa | Protein coding | CCDS43097 | A0A024R318 F8WAY7 | - | TSL:1, GENCODE basic, APPRIS P1, |
PARP3-201 | ENST00000398755.8 | 2337 | 533aa | Protein coding | CCDS43097 | Q9Y6F1-2 | NM_001003931.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PARP3-203 | ENST00000431474.6 | 2096 | 533aa | Protein coding | CCDS43097 | Q9Y6F1-1 | - | TSL:1, GENCODE basic, APPRIS P1, |
PARP3-209 | ENST00000498510.2 | 1952 | 533aa | Protein coding | CCDS43097 | A0A024R318 C9J9C7 | - | TSL:2, GENCODE basic, APPRIS P1, |
PARP3-208 | ENST00000486510.1 | 443 | No protein | Processed transcript | - | - | - | TSL:2, |
PARP3-204 | ENST00000470601.5 | 940 | No protein | Retained intron | - | - | - | TSL:2, |
PARP3-207 | ENST00000475782.1 | 771 | No protein | Retained intron | - | - | - | TSL:2, |
PARP3-205 | ENST00000470749.1 | 697 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | PARP3 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PARP3 had been KO in hela cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×