About Red-Cotton™ CRISPR Gene Editing Designer

Red Cotton™· CRISPR gene editing system (Red Cotton system), developed by Ubigene, is an automatic system with thousands of gene-editing big data, bioinformatics and IT technology.

You only need to input your target gene and cell line, and you will get the following information in a minute:

3sets of gene editing gRNA design schemes;

More than 800 cell line related parameters;

3000 successful cases of gene knockout;

Analysis and evaluation of gene knockout difficulty;

Analysis of transcripts and sequence complexity.

Make genome editing easier is the goal of Ubigene. Gene knockout schemes can be obtained in one minute via Red Cotton™. Ubigene can also provide gene-editing vectors, viruses and cell lines to meet the needs of different customers in an all-round way and make genome editing easier.

About CRISPR-U™ Cell Line
Technical principle

CRISPR-U™ (based on CRISPR/Cas9 technology), developed by Ubigene, is more efficient than general CRISPR/Cas9 in double-strand breaking, and CRISPR-U™ can greatly improve the efficiency of homologous recombination, easily achieve knockout (KO), point mutation (PM) and knockin (KI) in vitro and in vivo. With CRISPR-U™, Ubigene has successfully edit genes on more than 100 cell lines.

CRISPR/Cas9 recognizes the target sequence with gRNA, and guide Cas9 endonuclease to cut the upstream of PAM, resulting in the double-strand break (DSB) of the target site DNA. To repair the DSB, the cell uses its own DNA repair mechanism to add or delete or replace pieces of DNA sequences via Homology Directed Repair (HDR) or Non-Homologous End Joining (NHEJ).

Technical advantage
CRISPR-U:10X efficiency gene-editing

Exclusive innovation, 10 times more efficient in gene-editing.

100 types of knockin cell line

Successfully edit genes on more than 100 types of cell lines.

KO/PM/ KI

Easily generate knockout (KO), point mutation (PM) and knockin (KI) in vitro and in vivo.

100% mutation guarantee

CRISPR-U™ offers a 100% mutation guarantee. No mutation, no charge!

About Ubigene

Ubigene Biosciences is co-founded by biological academics and elites from China, the United States, and France. We are located in Guangzhou Science City, which serves as a global center for high technology and innovation. Ubigene Biosciences has 2000㎡ office areas and laboratories, involving genome editing, cell biology technology, and zebrafish research. We provide products and services for plasmids, viruses, cells, and zebrafish. We aim to provide customers with better gene-editing tools for cell or animal research.

Make genome editing easier is the goal of Ubigene. We developed CRISPR-U™ (based on CRISPR/Cas9 technology) which is more efficient than general CRISPR/Cas9 in double-strand breaking, and CRISPR-U™ can greatly improve the efficiency of homologous recombination, easily achieve knockout (KO), point mutation (PM) and knockin (KI) in vitro and in vivo. With CRISPR-U™, Ubigene has successfully edit genes on more than 100 cell lines.

Ubigene developed CRISPR-B™ which optimizes the microbial gene-editing vectors and process. The efficiency and accuracy are much higher than traditional methods. CRISPR-B™ can be used in gene editing of bacteria and fungi. Easily achieve microbial gene knockout (KO), point mutation (PM) and knockin (KI).

Ubigene has more than 400 types of primary cells, including epithelial cells, endothelial cells, smooth muscle cells and fibroblasts from different species, such as human, rat, and mouse. We can provide a validation report for each primary cell. Our primary cells have been widely used in many research institutes and pharmaceutical enterprises.

Pragmatism, efficiency, integrity are our business principles. We are committed to providing the best services and products to every customer who chooses us.

Genome Editing Platform

Focusing on the Application of CRISPR-U™ and CRISPR-B™ Gene Editing Technology

1. Provides various types of gene-editing vectors for different species.
2. Provides different virus packaging services, including lentiviruses, adenoviruses and adeno-associated viruses.
3. Provides high-quality services for gene knockout, point mutation, knockin cell lines and microbe.

Cell Biology Platform Cell Biology Platform

Focusing on primary cells

1. Provides over 400 types of primary cells.
2. Provides culture strategies and related products for different cell types.
3. Provides cell biology-related services such as cell isolation, extraction and validation.

  • CN

    +86 153 6067 3248 (Int'l)
    info@ubigene.com
    198 Kaiyuan Avenue, Floor 4, Huangpu District, Guangzhou, Guangdong, China

  • APAC

    Elecom: 001 800 3272 9252 (Toll free)
    Dacom: 002 800 3272 9252 (Toll free)

  • US

    195 Morgan Ave, Brooklyn, NY 11237, USA
    855 777 3210 (Toll free)

  • EU

    61 Avenue de la Marne 92130 Montrouge, France
    800 3272 9252 (Toll free)